United States securities and exchange commission logo June 16, 2023 Dr. Raluca Dinu Chief Executive Officer GigCapital5, Inc. 1731 Embarcadero Road., Suite 200 Palo Alto, California 94303 Re: GigCapital5, Inc. Form 10-K for the Fiscal Year Ended December 31, 2022 Filed March 31, 2023 Filed No. 001-40839 Dear Dr. Raluca Dinu: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services